Toluene
Also known as: methylbenzene, toluol, phenylmethane, antisal 1a
A volatile organic solvent derived from petroleum, widely used in nail polishes, nail treatments, and hair dyes. Toluene is a potent neurotoxin that affects the central nervous system and is one of the 'toxic trio' of nail polish ingredients (alongside formaldehyde and DBP).
1 = low concern, 10 = avoid
Risk by Usage Frequency
How risk changes depending on how often you use products containing Toluene.
Single nail application in a ventilated area poses limited risk.
Daily exposure (e.g., nail technicians) creates serious neurotoxicity and reproductive harm risk.
Extremely dangerous. Occupational toluene exposure is a documented cause of chronic neurological disease.
Health Risks
Neurotoxic: causes headaches, dizziness, fatigue, and cognitive impairment with repeated exposure.
EPA — Toluene hazard summary
Reproductive toxin: linked to developmental harm, spontaneous abortion, and birth defects in occupational studies.
American Journal of Industrial Medicine, 1999 — reproductive effects of toluene
Chronic inhalation exposure can cause permanent neurological damage, hearing loss, and kidney damage.
Global Regulatory Status
How toluene is regulated in cosmetics and personal care products around the world.
90% of countries with data ban or restrict this ingredient
Details
Permitted only in nail products at max 25% (Annex III).
Details
Only in nail products at max 25%.
Details
Only in nail products at limited concentrations.
Details
Permitted in nail products with limits.
Details
Restricted to nail products.
Details
Permitted in nail products at limited concentrations.
Details
Restricted to nail products per Safety Technical Standards.
Details
Only in nail products per ANVISA.
Details
Restricted to nail products at max 25%, aligned with EU.
Why Brands Use Toluene
Dissolves other ingredients and creates a smooth, even finish when nail polish is applied. Helps products dry quickly and evenly.
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Better alternatives exist. Brands choose toluene because it's cheap and effective, but safer options like ethyl acetate, butyl acetate, water-based nail polish formulations deliver similar results without the health concerns.
Toluene in Product Categories
Click a category to see every product containing toluene in that category, with full ingredient breakdowns.
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Safe Alternatives
What Numbrrrz Uses Instead
Numbrrrz does not formulate nail products, but all our formulations are free of toluene and petroleum-derived solvents.


